In this edition, we will bring you up to speed on AO VET activities over the past five months. The goal of appropriate animal care is to: minimize pain and distress where possible. Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. A. Pain or distress in mice is commonly expressed by dramatic changes in activity level and behavior. Complete the following nuclear equations. To share information with other regulatory agencies C. 8 percent C. Applicable federal mandates require the use of aseptic technique for survival surgery in mice. B. A. They do not apply to nonrecombinant ones. When picking up a mouse from a filter top cage, putting the wire bar lid sideways on the cage is helpful to: Reposition your grasp as you take the mouse out of the cage as it will tend to hold on to the wire bar lid. This section explains the subject of divorce law in New Jersey. They become more stringent Which of the following represents an appropriate technique for subcutaneous injections in mice? D. The Office of Laboratory Animal Welfare (OLAW). C. They become less important The overlap between groups has ______ in americas residential neighborhoods and workplaces. Write an expression using boolean variables a and b that evaluates to true when only one of a and b is true, and that is false if a and b are both false or both true. D. Animals should only be used in human clinical areas during weekday work hours. C. The veterinarian cannot exempt an animal, even for medical reasons. B. Sponsors an accreditation program mandated by U.S. Department of Agriculture (USDA) and Public Health Service (PHS). A Good practice when performing infectious disease work in animals includes working with hand covers; obtaining an antimicrobial sensitivity panel for the infectious agent; anesthetizing or sedating animals to reduce chances of accidental human needle sticks; and completing work in pairs. Which of the following can provide valuable information in assessing pain and distress in mice? A. Driving in the summer, winter, or rainy season may be to blame for the unpleasant odor inside the car. Check all that apply. B. What is the recommended method for the production of monoclonal antibodies? A. You can help Wikipedia by expanding it. B. C Sterile surgical techniquethe goal of which is to prevent contamination of the surgical siteis required for major and minor survival surgery. C. For rodents, individual postoperative care records are not usually maintained. We dont know a lot for sure about next season--the leaks have been few and You need to upload documents (e.g. Today, nearly 1,000 organizations worldwide (as of 31 December 2017) are accredited by AAALAC International. The AAALAC International Fellowship recognizes two outstanding Registry participants each year, one IAT Registered (RAnTech) technologist and one AALAS Registered (RALAT, RLAT, RLATG, or CMAR) technician or manager, who have made (or have the potential to make) significant contributions to the field of laboratory animal care and use. Minor Less painful alternatives to retroorbital blood collection are lateral saphenous, facial, and jugular vein blood collection. The 2015 memorandum of understanding between the NIH and NSF also mandates that organizations receiving NSF funding for animal research projects comply with the PHS Policy. It provides a mechanism for peer evaluation of animal care and use programs B. A microchip is injected subcutaneously with a hypodermic needle. D. Shares information with other regulatory agencies like U.S. Department of Agriculture (USDA) and Office of Laboratory Animal Welfare (OLAW). A straight needle is preferred for oral gavage in a 18 gram mouse because it prevents trauma to the esophagus. Give the BNAT exam to get a 100% scholarship for BYJUS coursesNo worries! Which of the following is an injectable anesthetic agent? B. A. Unsourced material may be challenged and removed. The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. Thermal support is not required in mice during anesthesia. A. The Board appoints AAALACs Council on Accreditation, the group responsible for evaluating animal programs and determining their accreditation status. C. The IACUC has regulatory authority to stop any animal activities to protect either animals or people. Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? C. The use of newer surgical techniques that result in less tissue trauma. When animals are used, AAALAC works with institutions and researchers to serve as a bridge between progress and animal well-being. To provide an assurance by an information specialist that no alternative to the proposed animal model exists. An agent that has high individual risk but low community risk would be in which Risk Group per the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules? Which of the following is an example of refinement per the three Rs of Russell and Burch? A. Which of the following activities would EXCLUDE an animal from USDA category B? Accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International has long been trumpeted as being the "gold standard" Conduct reviews of the animal care and use program on a semiannual basis, Institutional Animal Care and Use Committee. Let us have a look at your work and suggest how to improve it! D Organizations receiving funds from PHS agencies are required to comply with the PHS Policy. D. To search for procedures that may replace the use of animals, reduce the number of animals used, or refine the methodology to minimize animal pain or distress. An anesthetic overdose is an acceptable method. B. Research utilizing animals is a privilege, not a right, and the IACUC has the responsibility to ensure that research, testing, and educational activities involving the use of animals are performed according to the highest standards. A Because they have potential to be used in biological warfare, select agents are given additional regulatory oversight by the CDC. Which statement is true regarding venipuncture procedures in mice: A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. B. Signs announcing the use of animals in a clinical area must be posted for 14 days prior to use at high traffic areas throughout the hospital. Any time before the results are submitted for publication. Which of the following statements about identifying mice is NOT true? Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries? A. The Animal Welfare Regulations (AWR) do not currently apply to which of the following animals? True Over distension of the urinary and gall bladders. Which statement concerning survival experimental surgery is FALSE? Which of the following activities would place an animal in category E? Who is responsible for the humane treatment of experimental animals? B. Retroorbital blood collection from a mouse performed under anesthesia. Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (National Research Council, 1996). The exercise must take place outside the building. A. A. C. Sanitizing the area after use can be left to the night housekeeping crew, as long as they do the job within 12 hours. C The criteria used for intervention in research studies to prevent unnecessary pain and distress are called "humane endpoint criteria" because they describe when it is time to: euthanize an animal to prevent suffering; discontinue a painful procedure; and/or remove an animal from a study. Animal care and use regulations and guidelines require organizations to provide training in which of the following areas? D. Those organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. B Collection of blood by cardiac puncture can result in bleeding into the pericardial sac and tamponade (death), and should only be done terminally. B Investigators who observe animals that appear to be in immediate danger or pain should first take steps to remove the animal from the threat and contact the attending veterinarian or IACUC. D. A change in surgical anesthetic. B As the name implies, the Ag Guide is for agricultural animals used for agricultural (food and fiber) purposes. C. A change in personnel. C. Dry ice is an acceptable source of CO2 for euthanasia. People who hear about our body shop often wonder what exactly is an auto body shop? B. Sponsors an accreditation program Daily observations are usually recorded during the postoperative period. Performing or sponsoring research into alternatives to animal use for research and testing. D. Rodents and rabbits. For 50 years, the scientific community has activelyand voluntarilyparticipated in AAALAC's accreditation program. A. Remove the animal from the threat if safe to do so and contact the attending veterinarian or IACUC. The IACUC can exempt an animal for scientific reasons. C. The lateral saphenous vein is not accessible in the mouse. Anesthesia of the mouse can increase esophageal trauma caused by the gavage. In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. C. Sterile technique is optional for survival surgeries. Members of the Council are chosen to serve based on their extensive experience in the fields of veterinary medicine, laboratory animal science or animal research, and their commitment to humane animal care and use. If the investigator believes the event is due to misuse, mistreatment, or noncompliance, the details of the incident should be reported to the IACUC (or use another reporting method recommended by their organization), so that the incident can be reviewed and investigated (if warranted). A. C. Animals should be monitored during the postoperative period. A. Which of the following is TRUE regarding the Animal Welfare Regulations and duplication of experiments? What document provides the guidelines for working with infectious diseases in animal research? C. Dogs, pigs, and sheep. Mammaries become visible on the females around 9 days. Institutions receiving PHS money must follow the "Guide" (OLAW oversight) and those accredited with AAALAC are subject to triannual program review and facility visits. Why should an IP injection be made on the mouse's right side?
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